Moderna Patent 10703789

So glad this got released…

Moderna Patent 10703789

Wisenox, Member, Registered: 8/14/2021
Location: Mood:

posted on Mar, 9 2022 @ 10:12 PM
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I watched this Stew Peters interview with Karen Kingston.
The interview is very interesting and talks about things in the vaccine. I was looking up the documents she mentioned, and was actually taken back by the information in the Moderna patent.

Here is the Moderna patent Karen covers in the video:
Modified polynucleotides for the production of secreted proteins

The patent is a gold mine for everything we’ve been hearing about, and more. Its very lengthy because of the number of different uses it is designed for; Too much to cover here, however, there are a few I want to share.

First, the immune system evasion.
I posted about my theory that the innate immune response was being evaded through the mRNA capping process in the nucleus: Wisenox
The mRNA that comes from our nuclei is capped as ‘self’, and our innate immune system ignores it. Its part of the self-identity system that prevents us from attacking ourselves. It looks like I may have been on to something:

Traditionally, the basic components of an mRNA molecule include at least a coding region, a 5’UTR, a 3’UTR, a 5′ cap and a poly-A tail. Building on this wild type modular structure, the present invention expands the scope of functionality of traditional mRNA molecules by providing polynucleotides or primary RNA constructs which maintain a modular organization, but which comprise one or more structural and/or chemical modifications or alterations which impart useful properties to the polynucleotide including, in some embodiments, the lack of a substantial induction of the innate immune response of a cell into which the polynucleotide is introduced. As such, modified mRNA molecules of the present invention are termed “mmRNA”.

Anyone looking for an explanation for variants?

The term “polypeptide variant” refers to molecules which differ in their amino acid sequence from a native or reference sequence. The amino acid sequence variants may possess substitutions, deletions, and/or insertions at certain positions within the amino acid sequence, as compared to a native or reference sequence. Ordinarily, variants will possess at least about 50% identity (homology) to a native or reference sequence, and preferably, they will be at least about 80%, more preferably at least about 90% identical (homologous) to a native or reference sequence…

In some embodiments “variant mimics” are provided. As used herein, the term “variant mimic” is one which contains one or more amino acids which would mimic an activated sequence.

It may have the capability of producing its own variants. Is this how they planned on keeping it going forever?

They spell it out the variants in this one:

In one embodiment primary constructs or mmRNA may encode variant polypeptides which have a certain identity with a reference polypeptide sequence. As used herein, a “reference polypeptide sequence” refers to a starting polypeptide sequence.

This next portion, I suspect, is describing self-assembling tunable hydrogels, which Karen mentions:

polynucleotide, primary construct, and mmRNA of the invention can also be formulated as a nanoparticle using a combination of polymers, lipids, and/or other biodegradable agents, such as, but not limited to, calcium phosphate. Components may be combined in a core-shell, hybrid, and/or layer-by-layer architecture, to allow for fine-tuning of the nanoparticle so to delivery of the polynucleotide, primary construct and mmRNA may be enhanced.

And I believe this portion is describing PLA-PEG self-assembling hydrogels:

As a non-limiting example, the nanoparticle may comprise a plurality of polymers such as, but not limited to hydrophilic-hydrophobic polymers (e.g., PEG-PLGA)

After watching a couple self-assembling hydrogel videos on YouTube, I think hydrogels may even be the causative agent for Morgellons.

Also found a reference to magnetic properties:

Semi-Conductive and Metallic Nanoparticles:
The polynucleotides, primary constructs and/or mmRNAs of the present invention may be formulated in water-dispersible nanoparticle comprising a semiconductive or metallic material (U.S. Pub. No. 20120228565; herein incorporated by reference in its entirety) or formed in a magnetic nanoparticle (U.S. Pub. No. 20120265001 and 20120283503…)

We also learn that magnetic properties and PEG help get nucleic acids into cells:

A variety of methods are known in the art and suitable for introduction of nucleic acid into a cell, including viral and non-viral mediated techniques. Examples of typical non-viral mediated techniques include, but are not limited to, electroporation, calcium phosphate mediated transfer, nucleofection, sonoporation, heat shock, magnetofection, liposome mediated transfer, microinjection, microprojectile mediated transfer (nanoparticles), cationic polymer mediated transfer (DEAE-dextran, polyethylenimine, polyethylene glycol (PEG) and the like) or cell fusion.

Maybe this is why PEG is used in everything?

The entire patent is 278 pages as a pdf download, but the pages are scanned in as images in the version I found, so it isn’t searchable. The link above has full text.
I plan on reading it all some time, but after reading about the Internet of Bodies, Hydrogels, and digital ID’s today, I’d probably vomit.

If you read through it, post what you find.

Wisenox, Member, Registered: 8/14/2021
Location: Mood:

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a reply to: Wisenox

If the link to the patent doesn’t work, use this one and then select the full text link:
pubchem.ncbi.nlm.nih.gov…